Clinical Research

  • Read more: PRIM&R 2013 Advancing Ethical Research conference report: Paul Appelbaum on “therapeutic misconception”
    Article

    PRIM&R 2013 Advancing Ethical Research conference report: Paul Appelbaum on “therapeutic misconception”

    By Melissa Lopes Paul Appelbaum’s keynote address was both reflective and forward-looking in nature. He reflected back on his late ‘80s groundbreaking research introducing the concept of “therapeutic misconception” and challenged the audience to apply the results of such research to the examination of efforts to reduce this phenomenon.  Therapeutic misconception manifests itself in the incorrect…

  • Read more: FDA Suspension of Ponatinib: Serious Problem, Wrong Solution
    Article

    FDA Suspension of Ponatinib: Serious Problem, Wrong Solution

    By Richard Epstein Bad News On December 14, 2012, the US Food and Drug Administration granted an accelerated approval to the drug Ponatinib, which is used to treat patients with serious and life threatening forms of leukemia.  Unfortunately, the risks associated with the use of the drug have proved to be far greater than anticipated. …

  • Read more: PRIM&R 2013 Advancing Ethical Research conference report: Who is responsible for the body?
    Article

    PRIM&R 2013 Advancing Ethical Research conference report: Who is responsible for the body?

    By Lauren A. Taylor, Coordinator for Health and Religion in the Global Context, Harvard Divinity School and co-author of The American Health Care Paradox: Why Spending More Is Getting Us Less(PublicAffairs, 2013). Who is responsible for the stewardship of the body? What about the body’s tissue? Or its blood? While many people suggest that each individual owns…

  • Read more: PRIM&R 2013 Advancing Ethical Research conference report: Pluripotent Stem Cell Research: Let’s Discuss Informed Consent Lunch
    Article

    PRIM&R 2013 Advancing Ethical Research conference report: Pluripotent Stem Cell Research: Let’s Discuss Informed Consent Lunch

    By Melissa Lopes The DISCUSS project is designed to develop consensus recommendations for the use of stored biospecimens (originally consented for research) to: derive iPSC lines and deposit the derived lines in a cell bank or repository for widespread distribution. The project represents a formal collaboration of NIH, CIRM and the International Stem Cell Forum.…

  • Read more: Call for Abstracts, Petrie-Flom Center 2014 Annual Conference
    Article

    Call for Abstracts, Petrie-Flom Center 2014 Annual Conference

    By The Petrie-Flom Center The Petrie-Flom Center invites abstracts for its 2014 Annual Conference: “Behavioral Economics, Law, and Health Policy.” The conference will be held at Harvard Law School on May 2 and 3, 2014, and seeks to address the following questions: Are there features unique to health and health care that prevent individuals, groups,…

  • Read more: GIM: Informed consent for return of incidental findings in genomic research
    Article

    GIM: Informed consent for return of incidental findings in genomic research

    By Nicholson Price In the second installment of our new collaboration with Genetics in Medicine, we are highlighting an article released last week discussing informed consent for the return of incidental findings in genomic research. As whole-genome and whole-exome sequencing become increasingly common in medical research, the potential grows for identifying genetic findings that are…

  • Read more: Declaration of Helsinki – 2013 Edition
    Article

    Declaration of Helsinki – 2013 Edition

    By Holly Fernandez Lynch Ladies and gentlemen, we have a newly revised Declaration of Helsinki, just announced today in a special online communication from JAMA.  The revisions are accompanied by commentary from Paul Ndebele and Joe Millum, Dave Wendler, and Zeke Emanuel.  Take a look. Still no word on the ANPRM to the Common Rule,…

  • Read more: Popular Distrust of Health Science: A Crowdsourced Solution
    Article

    Popular Distrust of Health Science: A Crowdsourced Solution

    By Christopher Robertson Enjoying the fall foliage in Mt. Auburn Cemetery yesterday, I came across this marker for Benjamin Waterhouse.  In the overwrought language that is appropriate on a grave marker:  “In 1800 he introduced to the new world the blessing of vaccination.  Overcame popular prejudice and distrust by testing it on his own children…

  • Read more: Conference Announcement and Call for Abstracts, 2014 Petrie-Flom Center Annual Conference
    Article

    Conference Announcement and Call for Abstracts, 2014 Petrie-Flom Center Annual Conference

    By The Petrie-Flom Center The Petrie-Flom Center has released the description and call for abstracts for its 2014 Annual Conference: “Behavioral Economics, Law, and Health Policy.” The conference will be held at Harvard Law School on May 2 and 3, 2014, and seeks to address the following questions: Are there features unique to health and…

  • Read more: The Troubled Peer Review System, the Open Access Wars, & the Blurry Line Between Human Subjects Research & Investigative Journalism
    Article

    The Troubled Peer Review System, the Open Access Wars, & the Blurry Line Between Human Subjects Research & Investigative Journalism

    By Michelle Meyer Legal academics who work across disciplines sometimes find themselves in the uncomfortable position of explaining to their stunned colleagues the process by which second- and third-year law students, armed with author c.v.s, decide what gets published and where. Well, get ready to get your schadenfreude on. For the past 10 months, John…